C2C2-CO-like Transcription Factor Family

CO(CONSTANS) gene acts between the circadian clock and genes controlling meristem identity.In Arabidopsis, CO transcription factors defined by two conserved domains. The first is a zinc finger region near the amino terminus that resembles B-boxes, which regulate protein-protein interactions in several animal transcription factors. The second is a region of 43 amino acids near the carboxy terminus termed the CCT (CO, CO-like, TOC1) domain. Studies using green fluorescent protein fusions show that the CCT domain is involved in nuclear localization of the CO protein but must have an additional role because the late-flowering co-7 mutant, which has an altered CCT domain, correctly localizes the protein.
  • 80+ putative C2C2-CO-like TFs in soybean with (1) CCT domain of peptide, CDS, and cDNA sequences, CCT multiple sequence alignment; blast HSP, matched HSP seqeunecs and CCT domain based phylogeny tree; and with (2) ZF-B_Box domain of peptide, CDS, and cDNA sequences, multiple sequence alignment; blast HSP, matched zf-B_box sequences, and zf-B_box based phylogeny tree in Soy -- TFKB.
  • 31 C2C2-CO-like protein , and DNA sequences with annotations for soybean in PlantTFDB. Most are partial sequences.
    Last updated by Dr. Jeff Chen on July 20, 2009.