Dof Transcription Factor Family

Dof (DNA-binding with one finger) domain proteins are plant-specific transcription factors with a highly conserved DNA-binding domain, which presumably includes a single C(2)-C(2) zinc finger. During the past decade, numerous Dof domain proteins have been identified in both monocots and dicots including maize, barley, wheat, rice, tobacco, Arabidopsis, pumpkin, potato, and pea. Biochemical, molecular biological and molecular genetic analyses revealed that Dof domain proteins function as a transcriptional activator or a repressor involved in diverse plant-specific biological processes. Although more physiological roles of Dof domain proteins would be elucidated in future because of numerous Dof domain proteins in plants, it is already evident that the Dof domain proteins play critical roles as transcriptional regulators in plant growth and development. Notes: Dof is missed in PlnTFDB, and AtPID.
  • 87 predicated putative C2C2-Dof TF peptide, CDS, cDNA sequences; blast HSP, multiple sequence alignment, and phylogeny tree' in Soy - TFKB.
  • 34 C2C2-Dof protein and DNA sequences with annotations for soybean in PlantTFDB. Most are partial sequences.
    Last updated by Dr. Jeff Chen on July 20, 2009.