FHA Transcription Factor Family
The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognise phosphotyrosine with relatively high affinity. It spans approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich, which sometimes contain small helical insertions between the loops connecting the strands. To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not archaeal genomes. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples.

• Above description taken from TOBFAC
• More description in PlantTFDB
• More description in PlnTFDB

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2 FHA predicated TF peptide, CDS, and cDNA seqeuences, blast HSP, and multiple sequence alignment in Soy - TFKB.

14 FHA protein and DNA sequences with annotations for soybean in PlantTFDB. Most are partial sequences.

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Last updated by Dr. Jeff Chen on June 5, 2009.